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Proteinases, Their Extracellular Targets, and Inflammatory Signaling.

Pharmacological reviews

Ramachandran R, Altier C, Oikonomopoulou K, Hollenberg MD.
PMID: 27677721
Pharmacol Rev. 2016 Oct;68(4):1110-1142. doi: 10.1124/pr.115.010991.

Given that over 2% of the human genome codes for proteolytic enzymes and their inhibitors, it is not surprising that proteinases serve many physiologic-pathophysiological roles. In this context, we provide an overview of proteolytic mechanisms regulating inflammation, with a...

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Ramachandran R, Altier C, Oikonomopoulou K, et al. Proteinases, Their Extracellular Targets, and Inflammatory Signaling. Pharmacol Rev. 2016;68(4):1110-1142doi: 10.1124/pr.115.010991.
Ramachandran, R., Altier, C., Oikonomopoulou, K., & Hollenberg, M. D. (2016). Proteinases, Their Extracellular Targets, and Inflammatory Signaling. Pharmacological reviews, 68(4), 1110-1142. https://doi.org/10.1124/pr.115.010991
Ramachandran, Rithwik, et al. "Proteinases, Their Extracellular Targets, and Inflammatory Signaling." Pharmacological reviews vol. 68,4 (2016): 1110-1142. doi: https://doi.org/10.1124/pr.115.010991
Ramachandran R, Altier C, Oikonomopoulou K, Hollenberg MD. Proteinases, Their Extracellular Targets, and Inflammatory Signaling. Pharmacol Rev. 2016 Oct;68(4):1110-1142. doi: 10.1124/pr.115.010991. PMID: 27677721.
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Adolescent Alcohol Exposure Persistently Impacts Adult Neurobiology and Behavior.

Pharmacological reviews

Crews FT, Vetreno RP, Broadwater MA, Robinson DL.
PMID: 27677720
Pharmacol Rev. 2016 Oct;68(4):1074-1109. doi: 10.1124/pr.115.012138.

Adolescence is a developmental period when physical and cognitive abilities are optimized, when social skills are consolidated, and when sexuality, adolescent behaviors, and frontal cortical functions mature to adult levels. Adolescents also have unique responses to alcohol compared with...

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Crews FT, Vetreno RP, Broadwater MA, et al. Adolescent Alcohol Exposure Persistently Impacts Adult Neurobiology and Behavior. Pharmacol Rev. 2016;68(4):1074-1109doi: 10.1124/pr.115.012138.
Crews, F. T., Vetreno, R. P., Broadwater, M. A., & Robinson, D. L. (2016). Adolescent Alcohol Exposure Persistently Impacts Adult Neurobiology and Behavior. Pharmacological reviews, 68(4), 1074-1109. https://doi.org/10.1124/pr.115.012138
Crews, Fulton T, et al. "Adolescent Alcohol Exposure Persistently Impacts Adult Neurobiology and Behavior." Pharmacological reviews vol. 68,4 (2016): 1074-1109. doi: https://doi.org/10.1124/pr.115.012138
Crews FT, Vetreno RP, Broadwater MA, Robinson DL. Adolescent Alcohol Exposure Persistently Impacts Adult Neurobiology and Behavior. Pharmacol Rev. 2016 Oct;68(4):1074-1109. doi: 10.1124/pr.115.012138. PMID: 27677720; PMCID: PMC5050442.
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Botanicals and Their Bioactive Phytochemicals for Women's Health.

Pharmacological reviews

Dietz BM, Hajirahimkhan A, Dunlap TL, Bolton JL.
PMID: 27677719
Pharmacol Rev. 2016 Oct;68(4):1026-1073. doi: 10.1124/pr.115.010843.

Botanical dietary supplements are increasingly popular for women's health, particularly for older women. The specific botanicals women take vary as a function of age. Younger women will use botanicals for urinary tract infections, especially Vaccinium macrocarpon (cranberry), where there...

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Dietz BM, Hajirahimkhan A, Dunlap TL, et al. Botanicals and Their Bioactive Phytochemicals for Women's Health. Pharmacol Rev. 2016;68(4):1026-1073doi: 10.1124/pr.115.010843.
Dietz, B. M., Hajirahimkhan, A., Dunlap, T. L., & Bolton, J. L. (2016). Botanicals and Their Bioactive Phytochemicals for Women's Health. Pharmacological reviews, 68(4), 1026-1073. https://doi.org/10.1124/pr.115.010843
Dietz, Birgit M, et al. "Botanicals and Their Bioactive Phytochemicals for Women's Health." Pharmacological reviews vol. 68,4 (2016): 1026-1073. doi: https://doi.org/10.1124/pr.115.010843
Dietz BM, Hajirahimkhan A, Dunlap TL, Bolton JL. Botanicals and Their Bioactive Phytochemicals for Women's Health. Pharmacol Rev. 2016 Oct;68(4):1026-1073. doi: 10.1124/pr.115.010843. PMID: 27677719; PMCID: PMC5050441.
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Editor's note: pharmacological reviews to publish online before print.

Pharmacological reviews

[No authors listed]
PMID: 11121506
Pharmacol Rev. 2000 Dec;52(4):475.

No abstract available.

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Editor's note: pharmacological reviews to publish online before print. Pharmacol Rev. 2000;52(4):475
(2000). Editor's note: pharmacological reviews to publish online before print. Pharmacological reviews, 52(4), 475.
"Editor's note: pharmacological reviews to publish online before print." Pharmacological reviews vol. 52,4 (2000): 475.
Editor's note: pharmacological reviews to publish online before print. Pharmacol Rev. 2000 Dec;52(4):475. PMID: 11121506.
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Biosynthetic incorporation of metabolite analogues.

Pharmacological reviews

MATTHEWS RE.
PMID: 13590909
Pharmacol Rev. 1958 Sep;10(3):359-406.

No abstract available.

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MATTHEWS RE. Biosynthetic incorporation of metabolite analogues. Pharmacol Rev. 1958;10(3):359-406
MATTHEWS, R. E. (1958). Biosynthetic incorporation of metabolite analogues. Pharmacological reviews, 10(3), 359-406.
MATTHEWS, R E. "Biosynthetic incorporation of metabolite analogues." Pharmacological reviews vol. 10,3 (1958): 359-406.
MATTHEWS RE. Biosynthetic incorporation of metabolite analogues. Pharmacol Rev. 1958 Sep;10(3):359-406. PMID: 13590909.
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The measurement of pain; prototype for the quantitative study of subjective responses.

Pharmacological reviews

BEECHER HK.
PMID: 13431416
Pharmacol Rev. 1957 Mar;9(1):59-209.

No abstract available.

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BEECHER HK. The measurement of pain; prototype for the quantitative study of subjective responses. Pharmacol Rev. 1957;9(1):59-209
BEECHER, H. K. (1957). The measurement of pain; prototype for the quantitative study of subjective responses. Pharmacological reviews, 9(1), 59-209.
BEECHER, H K. "The measurement of pain; prototype for the quantitative study of subjective responses." Pharmacological reviews vol. 9,1 (1957): 59-209.
BEECHER HK. The measurement of pain; prototype for the quantitative study of subjective responses. Pharmacol Rev. 1957 Mar;9(1):59-209. PMID: 13431416.
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Correction to "Ketamine and Ketamine Metabolite Pharmacology: Insights into Therapeutic Mechanisms".

Pharmacological reviews

[No authors listed]
PMID: 30282701
Pharmacol Rev. 2018 Oct;70(4):879. doi: 10.1124/pr.116.015198err.

No abstract available.

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Correction to "Ketamine and Ketamine Metabolite Pharmacology: Insights into Therapeutic Mechanisms". Pharmacol Rev. 2018;70(4):879doi: 10.1124/pr.116.015198err.
(2018). Correction to "Ketamine and Ketamine Metabolite Pharmacology: Insights into Therapeutic Mechanisms". Pharmacological reviews, 70(4), 879. https://doi.org/10.1124/pr.116.015198err
"Correction to "Ketamine and Ketamine Metabolite Pharmacology: Insights into Therapeutic Mechanisms"." Pharmacological reviews vol. 70,4 (2018): 879. doi: https://doi.org/10.1124/pr.116.015198err
Correction to "Ketamine and Ketamine Metabolite Pharmacology: Insights into Therapeutic Mechanisms". Pharmacol Rev. 2018 Oct;70(4):879. doi: 10.1124/pr.116.015198err. PMID: 30282701.
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Inhaled .

Pharmacological reviews

Sriram K, Insel MB, Insel PA.
PMID: 34795026
Pharmacol Rev. 2021 Oct;73(4):488-526. doi: 10.1124/pharmrev.121.000356.

Inhaled long-acting

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Sriram K, Insel MB, Insel PA. Inhaled . Pharmacol Rev. 2021;73(4):488-526doi: 10.1124/pharmrev.121.000356.
Sriram, K., Insel, M. B., & Insel, P. A. (2021). Inhaled . Pharmacological reviews, 73(4), 488-526. https://doi.org/10.1124/pharmrev.121.000356
Sriram, Krishna, et al. "Inhaled ." Pharmacological reviews vol. 73,4 (2021): 488-526. doi: https://doi.org/10.1124/pharmrev.121.000356
Sriram K, Insel MB, Insel PA. Inhaled . Pharmacol Rev. 2021 Oct;73(4):488-526. doi: 10.1124/pharmrev.121.000356. PMID: 34795026.
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Regulation of Mitogen-Activated Protein Kinase Signaling Pathways by the Ubiquitin-Proteasome System and Its Pharmacological Potential.

Pharmacological reviews

Mathien S, Tesnière C, Meloche S.
PMID: 34732541
Pharmacol Rev. 2021 Oct;73(4):263-296. doi: 10.1124/pharmrev.120.000170.

Mitogen-activated protein kinase (MAPK) cascades are evolutionarily conserved signaling pathways that play essential roles in transducing extracellular environmental signals into diverse cellular responses to maintain homeostasis. These pathways are classically organized into an architecture of three sequentially acting protein...

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Mathien S, Tesnière C, Meloche S. Regulation of Mitogen-Activated Protein Kinase Signaling Pathways by the Ubiquitin-Proteasome System and Its Pharmacological Potential. Pharmacol Rev. 2021;73(4):263-296doi: 10.1124/pharmrev.120.000170.
Mathien, S., Tesnière, C., & Meloche, S. (2021). Regulation of Mitogen-Activated Protein Kinase Signaling Pathways by the Ubiquitin-Proteasome System and Its Pharmacological Potential. Pharmacological reviews, 73(4), 263-296. https://doi.org/10.1124/pharmrev.120.000170
Mathien, Simon, et al. "Regulation of Mitogen-Activated Protein Kinase Signaling Pathways by the Ubiquitin-Proteasome System and Its Pharmacological Potential." Pharmacological reviews vol. 73,4 (2021): 263-296. doi: https://doi.org/10.1124/pharmrev.120.000170
Mathien S, Tesnière C, Meloche S. Regulation of Mitogen-Activated Protein Kinase Signaling Pathways by the Ubiquitin-Proteasome System and Its Pharmacological Potential. Pharmacol Rev. 2021 Oct;73(4):263-296. doi: 10.1124/pharmrev.120.000170. PMID: 34732541.
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Structure-Based Virtual Screening for Ligands of G Protein-Coupled Receptors: What Can Molecular Docking Do for You?.

Pharmacological reviews

Ballante F, Kooistra AJ, Kampen S, de Graaf C, Carlsson J.
PMID: 34907092
Pharmacol Rev. 2021 Oct;73(4):527-565. doi: 10.1124/pharmrev.120.000246.

G protein-coupled receptors (GPCRs) constitute the largest family of membrane proteins in the human genome and are important therapeutic targets. During the last decade, the number of atomic-resolution structures of GPCRs has increased rapidly, providing insights into drug binding...

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Ballante F, Kooistra AJ, Kampen S, et al. Structure-Based Virtual Screening for Ligands of G Protein-Coupled Receptors: What Can Molecular Docking Do for You?. Pharmacol Rev. 2021;73(4):527-565doi: 10.1124/pharmrev.120.000246.
Ballante, F., Kooistra, A. J., Kampen, S., de Graaf, C., & Carlsson, J. (2021). Structure-Based Virtual Screening for Ligands of G Protein-Coupled Receptors: What Can Molecular Docking Do for You?. Pharmacological reviews, 73(4), 527-565. https://doi.org/10.1124/pharmrev.120.000246
Ballante, Flavio, et al. "Structure-Based Virtual Screening for Ligands of G Protein-Coupled Receptors: What Can Molecular Docking Do for You?." Pharmacological reviews vol. 73,4 (2021): 527-565. doi: https://doi.org/10.1124/pharmrev.120.000246
Ballante F, Kooistra AJ, Kampen S, de Graaf C, Carlsson J. Structure-Based Virtual Screening for Ligands of G Protein-Coupled Receptors: What Can Molecular Docking Do for You?. Pharmacol Rev. 2021 Oct;73(4):527-565. doi: 10.1124/pharmrev.120.000246. PMID: 34907092.
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L-Type Calcium Channel Blockers: A Potential Novel Therapeutic Approach to Drug Dependence.

Pharmacological reviews

Little HJ.
PMID: 34663686
Pharmacol Rev. 2021 Oct;73(4):127-154. doi: 10.1124/pharmrev.120.000245.

This review describes interactions between compounds, primarily dihydropyridines, that block L-type calcium channels and drugs that cause dependence, and the potential importance of these interactions. The main dependence-inducing drugs covered are alcohol, psychostimulants, opioids, and nicotine. In preclinical studies,...

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Little HJ. L-Type Calcium Channel Blockers: A Potential Novel Therapeutic Approach to Drug Dependence. Pharmacol Rev. 2021;73(4):127-154doi: 10.1124/pharmrev.120.000245.
Little, H. J. (2021). L-Type Calcium Channel Blockers: A Potential Novel Therapeutic Approach to Drug Dependence. Pharmacological reviews, 73(4), 127-154. https://doi.org/10.1124/pharmrev.120.000245
Little, Hilary J. "L-Type Calcium Channel Blockers: A Potential Novel Therapeutic Approach to Drug Dependence." Pharmacological reviews vol. 73,4 (2021): 127-154. doi: https://doi.org/10.1124/pharmrev.120.000245
Little HJ. L-Type Calcium Channel Blockers: A Potential Novel Therapeutic Approach to Drug Dependence. Pharmacol Rev. 2021 Oct;73(4):127-154. doi: 10.1124/pharmrev.120.000245. PMID: 34663686.
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G.

Pharmacological reviews

Ramms DJ, Raimondi F, Arang N, Herberg FW, Taylor SS, Gutkind JS.
PMID: 34663687
Pharmacol Rev. 2021 Oct;73(4):155-197. doi: 10.1124/pharmrev.120.000269.

Many of the fundamental concepts of signal transduction and kinase activity are attributed to the discovery and crystallization of cAMP-dependent protein kinase, or protein kinase A. PKA is one of the best-studied kinases in human biology, with emphasis in...

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Ramms DJ, Raimondi F, Arang N, et al. G. Pharmacol Rev. 2021;73(4):155-197doi: 10.1124/pharmrev.120.000269.
Ramms, D. J., Raimondi, F., Arang, N., Herberg, F. W., Taylor, S. S., & Gutkind, J. S. (2021). G. Pharmacological reviews, 73(4), 155-197. https://doi.org/10.1124/pharmrev.120.000269
Ramms, Dana J, et al. "G." Pharmacological reviews vol. 73,4 (2021): 155-197. doi: https://doi.org/10.1124/pharmrev.120.000269
Ramms DJ, Raimondi F, Arang N, Herberg FW, Taylor SS, Gutkind JS. G. Pharmacol Rev. 2021 Oct;73(4):155-197. doi: 10.1124/pharmrev.120.000269. PMID: 34663687.
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Showing 1 to 12 of 40 entries